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Contributory factors to primary angle closure glaucoma identified

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Eyes with acute primary angle closure glaucoma tend to have shallower anterior chamber depths, a greater anterior lens position and less cortical opacity than eyes not affected, according to a study.

Marcus C.C. Lim, MRCS(Ed), and colleagues treated 73 subjects with unilateral acute primary angle closure with sequential laser iridotomy in both eyes. The patients were predominantly Chinese (90%) and female (63%). The mean age was 61 years old.

Two weeks after surgery, the researchers compared lens thickness, lens position, relative lens position and degree and type of lens opacity between the affected and fellow eyes to determine if any of those variables contributed to the acute episode. Axial length and anterior chamber depth also were evaluated.

Significant differences between the affected and fellow eyes were found in the anterior chamber depth and lens position. Cortical opacity was greater in fellow eyes, and there was no difference in lens thickness, relative lens position or degree of lens opacity in the nuclear and posterior subcapsular regions.

The study is published in the June issue of Journal of Glaucoma.