August 16, 2002
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Conjunctival compression sutures effective in remodeling blebs

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CARDIFF, England — Conjunctival compression sutures and injection of autologous blood can help manage enlarged blebs, according to a study here. The techniques provide a "simple and effective means" of remodeling the filtration bleb that can be performed under topical anesthesia and does not hinder further bleb surgery, the study authors said.

Researchers here with University Hospital of Wales retrospectively analyzed 11 eyes of 11 patients with enlarged and dysmorphic filtration blebs who were managed with conjunctival compression sutures and subconjunctival injection of autologous blood. The injections were given a mean of 568 days following filtration surgery. Supplemental injections were required in eight patients, with three injections given to one patient. The highest intraocular pressure following injection was 25 mm Hg, with a mean of 17 mm Hg, and in none of the cases did blood enter the anterior chamber or parts of the filtration bleb bounded by the sutures.

The study is published in the August issue of British Journal of Ophthalmology.