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Complete excision of keratoacanthoma safest management strategy
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Clinically diagnosed keratoacanthoma can prove to be invasive squamous cell carcinoma in a significant percentage of cases, a study found. Complete excision of the tumor with margin control offers the safest management strategy, providing a definitive diagnosis, tissue conservation and a low recurrence rate, the study authors said.
Igal Leibovitch, MD, and colleagues at the Royal Adelaide Hospital in Australia reviewed the records of all patients with periocular tumors seen at their clinic during a 9-year period. They identified 12 patients who were clinically diagnosed with keratoacanthoma. The final histological diagnosis revealed two cases of invasive squamous cell carcinoma and 10 cases of keratoacanthoma. The lower lid was most commonly involved in cases of keratoacanthoma (50%). Six patients underwent Mohs’ surgery, and four were treated with excision under frozen section control.
No recurrence was seen during follow-up of a mean 21 months.
The study is published in the September issue of the British Journal of Ophthalmology.