Comparable results seen with keratectomy, amniotic membrane transplantation for bullous keratopathy
Cornea. 2010;29(9):976-979.
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Phototherapeutic keratectomy and amniotic membrane transplantation provide comparable relief for patients with painful bullous keratopathy and poor visual potential, a study said.
Researchers randomized 25 eyes of 25 patients into two groups: Thirteen eyes received phototherapeutic keratectomy (PTK) and 12 eyes received amniotic membrane transplantation (AMT).
At 6-month follow-up, both groups demonstrated a "significant decrease" in baseline symptoms. The investigators observed no difference in symptom scores between the groups.
All eyes in the PTK group achieved complete epithelialization at 2 weeks postop, while eight of 12 eyes in the AMT group achieved complete epithelialization (P = .023). However, the difference at 3 weeks was not significant.
In addition, one eye in the AMT group developed Staphylococcus epidermidis keratitis. No postop complications were reported in the PTK group.