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CNV removal can offer younger patients improved visual acuity

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STOCKHOLM, Sweden — Removal of submacular choroidal neovascularization does not seem to benefit patients over age 50 with age-related macular degeneration, but it can improve vision in younger patients without the disease, a study here suggests.

A review of patient records from all Swedish surgical centers performing removal of submacular choroidal neovascularization (CNV) identified 90 patients treated between 1992 and 1999 with a follow-up of 6 months or more. Results in 49 patients between the ages of 51 and 89 were compared with results in 41 patients between 6 and 49 years old. The older group had neovascular disease caused by age-related macular degeneration (AMD) and the younger group had CNV secondary to non-AMD causes.

Visual acuity at 6 months postoperatively was better in younger patients than in older patients. Marked visual improvement was seen in 29% of the non-AMD patients compared with none in the AMD group.

The study is published in the December issue of Acta Ophthalmologica Scandinavica.