Clinical features of polymorphous maculopathy syndrome described

Polymorphous maculopathy syndrome has symptoms similar to, but also different from, Harada disease and Best disease, according to a case study.

Clement Chan, MD, FACS, and colleagues at Southern California Desert Retina Consultants performed detailed ophthalmoscopy, fluorescein angiography, electrophysiology and optical coherence tomography on a patient with polymorphous maculopathy syndrome, or PMS.

Among the characteristics the authors found in this female patient were numerous small, yellowish lesions arranged in a honeycombed pattern at the level of the retinal pigment epithelium around the disk and the macula; a shallow macular detachment; and a perifoveolar yellow ring that appeared in both eyes. Antecedent upper respiratory infection and headaches and a positive serology for the coxsackie virus suggested the possibility of a virus-induced disorder.

The study is published in Retina.