November 10, 2011
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Clinical differences identified in anterior uveitis associated with rubella, herpes viruses


Ophthalmology. 2011;118(10):1905-1910.

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A study identified clinical differences in anterior uveitis associated with rubella, herpes simplex and varicella zoster viruses.

Clinical records of 106 patients with anterior uveitis were reviewed retrospectively, comparing data on demographic constitution, ophthalmologic characteristics and visual prognosis.

Anterior uveitis associated with rubella virus occurred in a younger age group at onset and followed a chronic course. It was also associated with cataract at presentation and heterochromia in 23% of patients.

Anterior uveitis associated with herpes simplex virus or varicella zoster virus was acute, occurred in older patients, and was associated with conjunctival redness, corneal edema, history of keratitis, and development of posterior synechiae.

The presence of vitritis was more commonly seen in anterior uveitis associated with rubella virus and varicella zoster virus; anterior chamber inflammation was more commonly seen with herpes simplex virus-associated anterior uveitis.

IOP greater than 30 mm Hg and glaucoma incidence were similar in all three groups. Visual prognosis for all three groups was favorable.