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Certain testing frequencies may be useful for evaluating early glaucoma damage

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Temporal frequency characteristics may be an indicator of visual field damage in patients with early open-angle glaucoma, according to a recent study.

Joseph Jy-Haw Yu and colleagues at the Tokyo Medical and Dental University, Japan, evaluated temporal frequency characteristics (TFC) obtained from visually evoked potentials (VEP).

According to the study, correlation coefficients between FDT thresholds and the TFC at 18 to 20 Hz in nonglaucomatous eyes was 0.03 centrally, 0.31 at 10°, 0.21 at 20° and 0.16 at 30°.

For eyes with early glaucoma, the correlation coefficient was 0.66 for the central area, 0.46 at 10°, 0.38 at 20°, and 0.35 at 30°.

The authors note that the correlation coefficients between frequency doubling technology (FDT) thresholds and TFC at temporal frequencies were relatively high at 18 to 20 Hz and 26 to 32 Hz. Also, the time needed to obtain PRBS-VEP data was approximately the same as that for FDT thresholds.

“The strong correlation between the two tests indicates that the FDT values and the high temporal frequency segments of the TFC may be useful as a preliminary indicator of visual damage in patients with early open-angle glaucoma,” the authors wrote in Documenta Ophthalmologica. “In addition, the strong correlation suggests that there was a preferential damage to the magnocellular system in glaucomatous eyes.”