July 30, 2009
1 min read
Save
This article is more than 5 years old. Information may no longer be current.
Certain serum concentrations may increase risk of nonproliferative diabetic retinopathy progression
Acta Ophthalmol. 2009;87(5):501-505.
You've successfully added to your alerts. You will receive an email when new content is published.
Click Here to Manage Email Alerts
Click Here to Manage Email Alerts
We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.
High serum concentration of the hemoglobin subtype HbA1c and lipoprotein a may lead to progression of nonproliferative diabetic retinopathy in patients with type 2 diabetes.
According to a review of 106 patients with nonproliferative diabetic retinopathy in a Japanese population followed for up to 2 years, 33 patients (31%) had disease progression. Progression of nonproliferative diabetic retinopathy within the study population was associated with HbA1c levels, systolic blood pressure, lipoprotein a levels and fibrinogen levels in blood serum.
Using multivariate logistic regression analysis, researchers identified two significant independent risk factors: HbA1c level (odds ratio = 1.74) and lipoprotein a level (odds ratio = 1.90).