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Celecoxib helpful in treatment of diffuse anterior scleritis
A COX-2 inhibitor can be a successful treatment alternative for diffuse anterior scleritis before the use of systemic immunosuppression, a study found.
Andrea M. Bauer, MD, PhD, and colleagues in Heidelberg, Germany, assessed the use of 200 mg to 800 mg of celecoxib daily in 24 patients with diffuse anterior scleritis. Dosing was determined based on degree of discomfort and clinical severity.
Of the 24 patients, 22 experienced a significant clinical improvement within an average of 5 days after starting celecoxib, reporting a complete loss of pain and scleral redness. After discontinuation of treatment three patients experienced a second attack of scleritis. Two patients experienced allergic exanthema.
The study is published in the June issue of the American Journal of Ophthalmology.