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CCT not a risk factor for hypotony-related complications after glaucoma surgery, study finds

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Increased central corneal thickness does not appear to be a risk factor for hypotony-related complications after glaucoma surgery, a study suggests.

"Pseudophakia and the magnitude of hypotony were predictors of hypotony maculopathy and choroidal effusion in this cohort," the study authors said in the July/August issue of Ophthalmic Surgery, Lasers & Imaging.

Sarah R. Wellik, MD, and colleagues at Bascom Palmer Eye Institute evaluated CCT and possible hypotony-related complications, including choroidal effusion or hypotony maculopathy, among 43 eyes of 43 patients who had an IOP of 7 mm Hg or less after either glaucoma filtration or drainage implant surgery. Specifically, 17 of these eyes had hypotony-related complications and 26 eyes had no complications.

Using forward stepwise multiple logistic regression, the investigators found that eyes with pseudophakia (P = .006) and lower postoperative IOP (P = .013) were significantly more likely to develop hypotony-related complications.

Mean CCT was comparable in eyes with hypotony-related complications (519 µm) and controls with no complications (525 µm), according to the study.