December 10, 2009
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Cataract surgery most successful at reducing IOP in POAG, PACG cases with high preop IOP

Can J Ophthalmol. 2009;44(6):705-710.

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Patients in glaucoma subsets with high preoperative IOP and medication use had the best success rates after cataract surgery, a study found.

"Primary small-incision cataract surgery using phacoemulsification and foldable intraocular lens implantation may be the procedure of choice in patients with medically controlled glaucoma and coexisting visually significant cataracts," the study authors said.

The retrospective evaluation looked at 48 patients with primary open-angle glaucoma (POAG) and 48 patients with primary angle-closure glaucoma (PACG). Patients had 2.75- to 3.5-mm limbal incision cataract surgery.

Success was defined as IOP between 6 mm Hg and 21 mm Hg, reduced medications and no additional glaucoma surgery.

The study found that for POAG cases, those eyes with the highest preoperative IOP of less than 31 mm Hg and with three or less medications "had a significantly higher probability of success."

For PACG cases, those eyes with the highest preoperative IOP of less than 42 mm Hg, three or less medications and peripheral anterior synechiae areas at 4 clock hours or less had the highest probability of success.