August 24, 2004
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Case report: Endophthalmitis a complication of vitrectomy with triamcinolone

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Triamcinolone acetonide-assisted pars plana vitrectomy can be complicated by postoperative endophthalmitis with unique signs and symptoms, according to a case study.

Takehiro Yamashita and colleagues at Kagoshima University in Japan described a case in which a 60-year-old man developed endophthalmitis after triamcinolone acetonide-assisted pars plana vitrectomy for diabetic macular edema. Preoperatively, the patient’s visual acuity was 20/200. Four days after surgery, endophthalmitis associated with anterior chamber hypopyon was noticed. The patient’s VA had deteriorated to hand motion. According to the authors, despite severe cell infiltration, the patient’s ciliary injection and ocular pain were not significant.

To resolve the endophthalmitis, surgeons performed an additional pars plana vitrectomy with irrigation using cefazolin and gentamicin. The endophthalmitis resolved soon after, and the patient’s VA improved to 20/100. Staphylococcus epidermidis was cultured from vitreous samples.

The case study is published in the August issue of Graefe’s Archive for Clinical and Experimental Ophthalmology.