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Careful management can preserve vision in children with intermediate uveitis
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Individually tailored immunosuppressive therapy may help preserve vision in at least one eye in children with idiopathic intermediate uveitis, a retrospective study suggests.
Rajni Jain, MRCOphth, and colleagues at Moorfields Eye Hospital in London reviewed the records of all patients under the age of 16 who presented with idiopathic intermediate uveitis between 1990 and 2001. From 114 cases of childhood uveitis, 45 eyes of 26 patients were identified with intermediate uveitis. The mean age at presentation was 10 years, with an average follow-up of 3 years. Of the eyes identified, 28 had “snowbanks” and five had cystoid macular edema at presentation, the authors said.
Six patients required no treatment, five needed topical treatment only, five were managed with orbital floor steroids alone and another two needed both orbital floor steroids and oral prednisolone. Systemic steroids were required for eight patients, four of which also needed cyclosporine.
Six children had successful outcomes and maintained a visual acuity of 6/9 in at least one affected eye.
The study is published in the February issue of Clinical & Experimental Ophthalmology.