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Capsular ‘shrink-wrap’ faster with silicone IOLs than acrylic

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FUKUOKA, Japan — Silicone IOL optics are completely apposed by the anterior and posterior capsules more quickly than acrylic IOL optics, according to a clinical study here. Silicone IOLs took about 8 days to complete capsular contact while acrylic IOLs took about 11 days. The difference was statistically significant.

Researchers here randomized 32 patients scheduled to undergo phacoemulsification to either silicone or acrylic IOL implantation. Contact of the anterior and posterior lens capsule with the IOL optic surface was evaluated using Scheimpflug photography at days 3, 5, 7, 9, 11, 14, 21 and 28 postoperatively. Anterior chamber depth was measured, and the day each capsule was completely apposed to the IOL optic was noted.

The anterior capsule was in contact with the IOL optic on the same day or earlier than the posterior capsule in all patients. Complete apposition of the IOLs was achieved earlier with silicone than with acrylic by both the anterior capsules (P < .0001) and the posterior capsules (P = .0339).

No significant change in mean anterior chamber depth was observed with the silicone IOLs. Significant anterior shift was noted with the acrylic IOLs.

The study is published in the August issue of Ophthalmology.