September 26, 2005
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C-reactive protein may have link to normal tension glaucoma

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Higher levels of C-reactive protein may be associated with normal tension glaucoma, according to a study. In addition, researchers believe a vascular inflammatory process is involved in the etiology of this type of glaucoma.

Igal Leibovitch, MD, and colleagues compared 20 patients with normal tension glaucoma to 30 healthy age-matched control subjects who had no history of ocular disease. Plasma C-reactive protein levels of all study participants were determined. Both groups had similar demographic parameters such as age, sex and body mass.

Plasma C-reactive protein levels were significantly higher in the normal tension glaucoma cases than in controls. The mean plasma C-reactive protein level was significantly elevated in the patients with glaucoma compared with the controls.

The study is published in the October issue of Journal of Glaucoma.