September 12, 2006
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C-Flex IOL has low PCO rate at 2 years

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LONDON — A square-edged hydrophilic acrylic IOL shows good functional results, with a low incidence of posterior capsular opacification at 2 years' follow-up, according to a surgeon speaking here.

Yutaro Nishi, MD, reviewed results with the C-Flex IOL from Rayner. He presented the results at the European Society of Cataract and Refractive Surgeons annual meeting.

The C-Flex IOL has an "enhanced edge design" compared to its predecessor, the CentreFlex, Dr. Nishi said. The CentreFlex had a sharp optic edge design except at the optic-haptic junction, which could act as a "gateway" for lens epithelial cell proliferation onto the posterior capsule.

The redesigned C-Flex IOL has a sharp edge all the way around the optic to prevent cell proliferation, he said.

Dr. Nishi and colleagues in Heidelberg, Germany, implanted the C-Flex lens in 42 eyes as part of a study for U.S. Food and Drug Administration approval. At 2 years, mean best corrected visual acuity averaged 0.83 in these eyes, with almost no PCO development, Dr. Nishi said.

"It seems the 360° enhanced edge delayed PCO development," he said.