June 17, 2004
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Biotech drug may help treat wet AMD, animal study finds

An antisense drug designed to block growth hormone receptor expression has been found to ward off wet age-related macular degeneration in mice, the drug's developer said in a press release. ATL1103 was tested on mice at the University of Queensland in Australia, according to Antisense Therapeutics. By targeting growth hormone receptors, ATL1103 reduces levels of insulin-like growth factor-1, according to the press release.

Development of AMD has been linked to excessive levels of IGF-1, as has diabetic retinopathy, the company said.

Antisense Therapeutics noted the drug will enter human trials soon.