March 25, 2009
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Aspheric IOL selection based on wavefront significantly reduces spherical aberration

J Refract Surg. 2009;25(1):12-20.

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Customized selection of aspheric IOLs based on corneal wavefront measurement significantly reduced spherical aberration.

All patients underwent phacoemulsification and received one of three aspheric IOLs. Choice of aspheric IOL for each eye was based on preoperative corneal spherical aberration and labeled IOL spherical aberration yielding the closest possible sum to zero. Corneal spherical aberration was measured at the 6-mm optical zone.

Mean preoperative corneal spherical aberration was +0.26 ± 0.089 µm. Mean postoperative spherical equivalent refraction was –0.32 D ± 0.54 D. Ninety-three percent of eyes had total ocular spherical aberration of less than ±0.1 µm.

Total postoperative ocular spherical aberration was –0.013 ± 0.072 µm. For all patients, mean absolute predictive error was 0.058 µm ± 0.056 µm.

“Several factors may influence these results and should be considered in our evaluation: effective postoperative pupil size, tilt or decentration of the IOL and surgically induced spherical aberration,” the study said.

Limitations of the study included a lack of data on postoperative topography and the absence of psychometric testing or contrast sensitivity measurements.