This article is more than 5 years old. Information may no longer be current.

Appropriate intervention may control IOP after DSAEK

Am J Ophthalmol. 2011;152(1):48-54.

Add topic to email alerts

Receive an email when new articles are posted on

Please provide your email address to receive an email when new articles are posted on .

Subscribe

Added to email alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

Back to Healio

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Back to Healio

It is possible to control postop IOP after Descemet's stripping automated endothelial keratoplasty with prompt and appropriate intervention, a study found.

"These eyes should be monitored carefully, and IOP-lowering therapy should be instituted promptly to prevent possible progression of glaucoma," the study authors said.

The retrospective study analyzed 47 consecutive eyes with pre-existing glaucoma or ocular hypertension that underwent DSAEK at the Singapore National Eye Centre from January 2007 through May 2009. The primary outcome measures were graft failure and the need for additional IOP-lowering treatment after DSAEK.

Mean patient age was 66.6 years; mean follow-up time was 27.3 months.

Preop visual acuity was 6/60 or worse in 32 patients (68.1%) and 6/12 or better in one patient. Postoperatively, 24 patients (51.1%) had a visual acuity of 6/12 or better at last follow-up. Compared to preop visual acuity, the difference was statistically significant (P < .001). Graft failure occurred in eight cases (17%) at a mean of 12.8 months. Sixty-two percent of eyes required additional IOP-lowering treatment; 28% required filtration surgery.

Glaucomatous eyes that had not undergone prior filtration surgery were more than 10 times more likely to require additional IOP-lowering therapy than eyes that had undergone prior trabeculectomy (P = .002). Eyes that underwent additional intraoperative procedures during DSAEK were 18 times more likely to require IOP-lowering treatment than eyes that did not undergo intraoperative procedures (P = .008).