September 15, 2011
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Aphakic keratoprosthesis implantation yields better refractive outcomes


J Cataract Refract Surg. 2011;37(9):1615-1622.

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Aphakic patients who underwent keratoprosthesis implantation had better refractive outcomes than pseudophakic patients who had the procedure, a study found.

"As corneal surgeons, we are often faced with an unstable posterior chamber IOL without adequate capsule support or an anterior chamber IOL at the time of keratoprosthesis implantation," the study authors said.

The retrospective study included 15 patients with posterior chamber IOLs who underwent implantation of a Boston type 1 keratoprosthesis and IOL explantation. A control group comprised 10 patients with stable posterior chamber IOLs who underwent only implantation of a Boston type 2 keratoprosthesis.

The researchers evaluated postoperative refractive error, uncorrected and corrected visual acuities, and intraoperative and postoperative complications. Patients underwent complete examinations 1 day, 1 week and 1 month postoperatively. Patients with stable IOLs were examined subsequently every 3 to 4 months.

Mean follow-up after surgery implantation was 21.93 months in the aphakic group and 35.7 months in the pseudophakic group.

Study results showed that median refractive error was 0 D in the aphakic group and -3.25 D in the pseudophakic group. Mean spherical equivalent refractive error was -0.66 D in the aphakic group and -3.25 D in the pseudophakic group. The between-group difference was statistically significant (P = .04).

Both groups had low complication rates.