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Antibiotic treatment of IOLs can reduce bacterial adherence, study suggests
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HYDERABAD, India — The incidence of post-cataract endophthalmitis might be reduced by treating the IOL with an antibacterial agent before implantation, a small study here suggests. Surgeons who treat IOLs with vancomycin might be able to reduce the levels of bacterial adherence to PMMA IOLs, the study authors said.
Taraprasad Das, MD, and colleagues here with the Endophthalmitis Research Group soaked 12 PMMA IOLs in solutions of Staphylococcus epidermidis in variable loads. The lenses were rinsed or rinsed and vortexed and then cultured. A second set of 12 IOLs were treated with vancomycin (10 mg/mL), randomized to before and after treatment with S. epidermidis.
The researchers found the IOLs treated with vancomycin had less S. epidermidis adherence than lenses not treated with the antibacterial agent.
The study can be found in the April issue of Journal of Cataract & Refractive Surgery.