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AMD severity may be influenced by lipid levels, study suggests

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Dyslipidemia may be directly associated with severity of age-related macular degeneration, according to a recent cross-sectional study. However, due to the study’s explorative nature, the results should be interpreted cautiously, the authors wrote.

Dr. A. Wachter and colleagues in Münster, Germany, divided 730 patients who were originally part of the Münster Age and Retina Study into four groups based on their AMD form.

According to the study, several factors correlated with the severity of AMD. These include a significant decrease in high-density lipoprotein (P = .087), significant increases in the high-density lipoprotein/low-density lipoprotein quotient (P = .0007), and nonsober triglyceride values (P = .0058). The study found no statistically significant difference in risk factors for arteriosclerosis, such as diabetes, body-mass-index and hypertension. However, the number of patients who smoked increased significantly with the severity of AMD (P = .02).

The study was published in Der Ophthalmologe.