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Amblyopia onset determines fellow eye responses, surgeon says

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LONDON — The fellow eye of patients with amblyopia may react differently depending on when the patient developed the amblyopia, John Sloper, FRCS, FRCOphth, told attendees here at the Moorfields Bicentenary scientific meeting.

Prof. Sloper and colleagues studied 24 adult patients who had amblyopia onset after 18 months of age. Initial visual acuity ranged from 6/9 to 1/60.

In patients with early onset amblyopia, fellow eyes showed reduced latency when compared with control eyes. In those with late onset amblyopia, the fellow eye reacted similarly to a control eye, Prof. Sloper said.

“The fellow eye also reacts quicker to stimulus in those with early onset amblyopia than in control eyes,” he said. Late onset amblyopia fellow eyes showed a “significantly reduced contrast sensitivity when compared with a normal eye,” he said.

“In short, fellow eyes have altered responses,” he said. “Fellow eye changes are a direct result of the time of amblyopia onset.”

He stressed that patching is responsible for some, but not all, abnormalities in the fellow eye.