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Amblyopia ‘major limiting factor’ in congenital cataract success

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Amblyopia is a major limiting factor in the successful treatment of unilateral cataract or unilateral aphakia, according to a study. The emphasis for surgeons should be on accurate evaluation of visual progression, the study authors said.

Michael C. Struck, MD, and Jim N. VerHoeve, PhD, at the University of Wisconsin Madison, used Sweep Visual Evoked Potential (SVEP) to follow the visual acuity development of 36 patients until they reached the age of 3. Of the patients, 18 had unilateral cataract, nine had bilateral cataract, and nine were control subjects.

Interocular acuity differences on the SVEP test allowed for modulation of the occlusion schedule in the first 2 years of life. “In many instances, this allowed for a significant reduction in occlusion therapy,” the researchers said. The SVEP results were “highly correlated” to the final subjective VA, they added.

The study is published in the Journal of American Association for Pediatric Ophthalmology and Strabismus.