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Administering intravitreal steroid injection 1 week before PDT has similar visual outcome as same-day treatment

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Administering intravitreal triamcinolone acetonide in eyes with exudative age-related macular degeneration 1 week before photodynamic therapy may result in similar visual outcomes as same-day treatment, according to a retrospective study.

Daniel B. Roth, MD, and colleagues compared visual acuity outcomes after administering combined intravitreal triamcinolone acetonide and PDT with verteporfin to 61 eyes with exudative AMD. Specifically, 31 eyes received treatment 1 week before PDT, and 30 eyes received treatment followed by PDT on the same day.

"There was no significant difference in visual acuity between the groups at baseline (P = .084), 6 to 12 weeks of follow-up (P = .085) or 1 year of follow-up (P = .093)," the authors said.

In addition, there was no significant difference in visual acuity outcomes at 6 to 12 weeks (P = .44) or 1 year (P = .28) after adjusting for baseline visual acuity, spot size, lesion type, age and gender, the authors noted.

The study is published in the January/February issue of Ophthalmic Surgery Lasers & Imaging.