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Acute postop endophthalmitis after triamcinolone injection ‘uncommon’
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Acute postoperative endophthalmitis following injections of intravitreal triamcinolone acetonide is “a relatively uncommon event,” a review of more than 1,000 cases indicates.
Andrew C. Westfall, MD, and colleagues reviewed 1,006 consecutive eyes that received intravitreal triamcinolone acetonide injections at two institutions in Texas. None of the eyes developed acute, culture-positive postoperative endophthalmitis during the 6 weeks following injection. One patient developed acute culture-negative postop endophthalmitis 4 days after receiving intravitreal triamcinolone injection. Presenting symptoms were decreased vision and acute conjunctival erythema, mild anterior chamber cellular reaction, trace flare and mild vitritis. Pain and hypopyon were absent, the study authors noted.
The researchers attribute the low incidence (0.1%) of endophthalmitis in their study “to our sterile approach that was prompted by previously associating corticosteroid injections with endophthalmitis.”
The study is published in the August issue of Archives of Ophthalmology.