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Acuity, contrast sensitivity not always correlated in eyes with AMD

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Visual acuity and contrast sensitivity do not always show the same progression in eyes with visual function loss due to neovascular age-related macular degeneration, but there is a moderate correlation between the two measurements, according to a German study.

Caren Bellmann and colleagues at the University of Heidelberg assessed VA and contrast sensitivity (CS) changes over time in 205 patients with neovascular AMD enrolled in the Radiation Therapy for Age-Related Macular Degeneration study.

At baseline, mean VA was 55.6 letters on the Early Treatment Diabetic Retinopathy Study chart, and mean CS was 22.8 letters on the Pelli-Robson chart. Characteristics and presence of choroidal neovascularization in the fellow eye as well as gender and age were evaluated. At 2 years follow-up, the mean VA loss was 23.6 letters, and CS reduction was 9 letters. Proportional hazard models did not show any apparent influence of the type of CNV in the fellow eye on changes in VA or CS.

The study is published in the December issue of Graefe’s Archive for Clinical and Experimental Ophthalmology.