December 23, 2003
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Acrylic adhesive similar to absorbable sutures for conjunctival closure

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An acrylic adhesive shows results similar to absorbable sutures for conjunctival sealing, according to an animal study.

Jorge Alió, MD, and colleagues measured the clinical efficacy of the acrylic adhesive, ADAL-2 (BTG), in albino rabbits. The researchers performed a conjunctival peritomy and dissection and created a conjunctival flap in the rabbit eyes, and the flaps were closed with one of two methods: either the acrylic tissue adhesive or suturing with 8-0 polyglactin. Clinical efficacy of the closure of the conjunctival wound as well as clinical and histopathologic tolerance were evaluated at 1, 7, 28 and 42 days postoperatively.

No significant differences in clinical or histopathologic tolerance were noted between the two closure methods. No presence of the adhesive was seen at 28 days postop.

The study is published in the November/December issue of Ophthalmic Research.