January 19, 2011
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Accommodating IOL increases depth of focus but refractive predictability remains unknown

Michael C. Knorz, MD
Michael C. Knorz

A dual-optic accommodating IOL has shown promising early results, a speaker said at Hawaiian Eye 2011.

Michael C. Knorz, MD, OSN Europe Edition Board Member, shared data and personal experience related to the Synchrony IOL (Abbott Medical Optics). The Synchrony is undergoing U.S. Food and Drug Administration clinical trials and has earned CE certification in the European Union.

The Synchrony features a +32 D anterior optic and a 6-mm variable minus-powered posterior optic. In theory, the +32 D optic provides about 2.5 D of accommodation with 1 mm of anterior lens movement.

Dr. Knorz cited a 2007 study by Ivan L. Ossma-Gomez, MD, MPH, and colleagues showing that, at 6 months, the Synchrony provided an accommodative range on a defocus curve of 3.22 D, while a monofocal control IOL afforded a range of 1.65 D. The study, published in the Journal of Cataract and Refractive Surgery, included 24 eyes.

Another study, by Angela Ehmer, MSc, and colleagues, also published in the Journal of Cataract and Refractive Surgery, showed that the Synchrony provided 1 D of accommodation at 54 months.

Dr. Knorz said he has implanted eight Synchrony IOLs since October. He said the preloaded injector enabled easy and controlled lens implantation, albeit through a 3.8-mm incision that required a suture. The lens has increased depth of focus by 2.8 D.

The Synchrony has been shown to yield early postoperative myopia. However, long-term refractive predictability is unknown and further study is merited, Dr. Knorz said.

  • Disclosure: Dr. Knorz is a consultant for Abbott Medical Optics, Alcon Laboratories and LenSx Lasers.

Hawaiian Eye and Retina 2012 will be held January 15-20 at the Grand Wailea Resort & Spa in Maui. Learn more at OSNHawaiianEye.com or RetinaMeeting.com.