Pediatric Neurology News

DENVER — Losmapimod treatment for those with facioscapulohumeral muscular dystrophy led to no serious adverse events across three clinical trials, according to a poster at the American Academy of Neurology annual meeting.

Among adolescents with focal epilepsy, nonmotor seizures are more often missed or misdiagnosed compared with motor seizures, according to research presented in Neurology.

The FDA has granted regenerative medicine advanced therapy designation to an intrathecally delivered AAV9 gene transfer therapy to treat younger individuals with Rett syndrome, according to the manufacturer.

DENVER — A panel of four experts discussed different aspects of the ways brain health and climate change are linked at the American Academy of Neurology annual meeting.

DENVER — Children from underrepresented groups with migraine received fewer diagnoses, imaging, tests and medication compared with their white counterparts, according to a poster at the American Academy of Neurology annual meeting.

A study identified late or varied bedtimes as risk factors for worse grades and behavioral issues among high school students, according to results published in Sleep.

Seizure frequency was reduced as much as 85% at 3 months in young patients with Dravet syndrome treated with a proprietary antisense oligonucleotide, according to results of phase 1/2a studies released by the manufacturer.

The FDA has granted clearance to a transcranial magnetic stimulation device as an adjunctive treatment for major depressive disorder in patients aged 15 to 21 years, according to the manufacturer.

The FDA has approved Lenmeldy as the first gene therapy to treat children with pre-symptomatic late infantile, pre-symptomatic early juvenile or early symptomatic early juvenile metachromatic leukodystrophy.

Enzyme-replacement therapy may slow disease progression and improve motor function in children with Pompe disease, according to a poster from the 2024 Muscular Dystrophy Association Clinical & Scientific Conference.