Pediatric Neurology News

A study of more than 50,000 children born over a 14-year period in Denmark found that children born to mothers who were exposed to higher levels of lithium in their drinking water were moderately more likely to develop autism.

Treatment with pitolisant demonstrated significant efficacy in reducing excessive daytime sleepiness and cataplexy in children aged 6 years and older, according to research presented in The Lancet Neurology.

Delandistrogene moxeparvovec improved motor function and was well-tolerated 4 years after treatment in a small cohort of children with Duchenne muscular dystrophy, according to a poster at the 2023 MDA Clinical & Scientific Conference.

Treatment with givinostat was associated with improvement in mobility and physical function compared with placebo in ambulant boys with Duchenne muscular dystrophy, according to a poster at the 2023 MDA Clinical & Scientific Conference.

Stoke Therapeutics Inc. announced the FDA will allow administration of a higher single dose of its investigational drug STK-001 in its ongoing phase 1/2a MONARCH study of children and adolescents with Dravet syndrome.

Results of a randomized, double-blind trial showed that hyperbaric oxygen therapy improved cognitive and behavioral function in children experiencing persistent post-concussion syndrome, as published in Scientific Reports.

Neurological abnormalities were not highly associated with pigmentary mosaicism, with only 14.8% of patients with the disorder exhibiting developmental delay, seizures or microcephaly, according to a study.

Regions of the brain associated with executive function in adults are similarly recruited in children as young as 4 years, according to findings published in the Journal of Neuroscience.

The FDA has approved Lamzede, an enzyme replacement therapy for non-central nervous system manifestations of alpha-mannosidosis in adult and pediatric patients, Chiesi Global Rare Diseases announced in a press release.

Black children on average undergo more family conflict, material hardship and traumatic events than white children, resulting in differences in gray matter volume in key brain regions and disorders such as PTSD, data show.