Parkinson's Disease/Movement Disorders News

PHILADELPHIA — Consideration of multiple factors among patients, families and health care providers drive the process of diagnosing preclinical or prodromal neurologic disease, which should be tailored to the individual, a speaker said.

PHILADELPHIA — Patients with a psychotic-spectrum disorder may be more likely to develop Parkinson’s disease, especially if they have an additional diagnosis of anxiety, according to a poster presentation.

The FDA has accepted a new drug application from Neurocrine Biosciences Inc. for its novel granule formulation of oral Ingrezza capsules, for those with tardive dyskinesia or chorea associated with Huntington’s disease.

PHILADELPHIA — Biomarkers are enabling the detection of neurological diseases up to 3 decades before a diagnosis would typically occur, Jane Paulsen, PhD FANA, says in this Healio video.

Case-control and cohort analyses showed dysphasia, gastroparesis, irritable bowel syndrome without diarrhea and constipation may be associated with an increased risk for Parkinson’s disease, according to research in Gut.

The B-glucocerebrosidase protein was a novel risk factor for Parkinson’s disease in African or African admixed populations and may assist in targeted treatments for these populations, according to a study published in The Lancet Neurology.

A Southern California-based bioscience firm has announced additional positive data on FDA-approved Ingrezza capsules to treat adults with chorea associated with Huntington’s disease.

Positive data from a phase 1 clinical trial for bemdaneprocel, a stem cell-derived investigational therapeutic for treating Parkinson’s disease, have been announced by its manufacturer.

Although generally safe and well-tolerated, venglustat treatment for adults with GBA-1 associated Parkinson’s disease was not superior to placebo after 1 year, per data from the Lancet Neurology.

Individuals with Parkinson’s disease present with reduced thickness of two key components of the retina, which may indicate retinal optical coherence tomography as a vital tool in early disease detection, data show.