Transplantation News

BOSTON — Female kidney transplant recipients who conceived between the ages of 18 and 25 years had higher rates of rejection and graft loss, as well as higher serum creatinine post-pregnancy, than women who were older at the age of conception, according to a speaker at the American Transplant Congress.

BOSTON — For transplant recipients with type 2 diabetes, delayed graft function was more common in those with higher BMIs and allograft survival was lowest in those categorized as obese or underweight, according to research presented at the American Transplant Congress.

BOSTON — Kidney transplant recipients have a substantially greater risk of cardiovascular mortality than the general population, and excess risk is higher for women than men, according to a speaker at the American Transplant Congress.

BOSTON — Although allograft survival was lower in dual kidney transplant when compared with standard criteria donor transplant, it was significantly higher in dual kidney transplant recipients than in expanded criteria donor recipients, according to research presented at the American Transplant Congress.

BOSTON — A donor-derived cell-free DNA test that considers donor-specific antibodies may help predict antibody-mediated rejection in patients younger than 21 years of age, according to research presented at the American Transplant Congress.

BOSTON — After barriers to participating in the care of patients awaiting kidney transplant were reported by friends and family, researchers began investigating ways to empower these social support networks and to increase their engagement in the transplant process, according to Allyson Hart, MD, MS, of Hennepin County Medical Center in Minnesota.

BOSTON — A test that uses donor-derived cell-free DNA accurately discriminated rejection from non-rejection in kidney transplant recipients and was particularly effective in the discrimination of antibody-mediated rejection, according to research presented at the American Transplant Congress.

BOSTON — Although only younger donor age was found to be significantly associated with improved survival, research presented here showed patients who received combined heart-kidney transplants had better overall survival and rejection-free graft outcomes at 1 year, 5 years and 10 years post-transplant compared with patients who had heart transplants alone.

Kidney transplantation is more likely to fail for adults with diabetic kidney disease and diabetic neuropathy who then present with a diabetic foot ulcer after surgery vs. those without foot ulcer, according to findings presented at the American Diabetes Association 79th Scientific Sessions. In addition, common factors for post-transplant diabetic foot ulcers include a prior history of the condition as well as previous peripheral arterial disease.

BOSTON— Results from a study presented here confirmed the association between the gut microbiome and the development of viral infections from stem cell transplant recipients to solid organ graft recipients and reinforced the need to monitor the risk of infection closely.