Infection Control News

A study on deceased donor kidneys has identified hepatitis C viremia, the need for dialysis, hematopoietic cell transplant and exposure to antibiotics with a narrow gramnegative spectrum as the top risks for infection.

BOSTON— Results from a study presented here confirmed the association between the gut microbiome and the development of viral infections from stem cell transplant recipients to solid organ graft recipients and reinforced the need to monitor the risk of infection closely.

BOSTON — Neutrolin, an investigational new drug containing taurolidine, was shown to reduce catheter-related bloodstream infections among patients with ESRD who were on hemodialysis via a central venous catheter, according to data presented at the National Kidney Foundation Spring Clinical Meetings.

Mycophenolic acid C12 to be associated with the 12-hour area under the curve, and linked to renal flare, infection and anemia, according to findings published in Nephrology Dialysis Transplantation.

The FDA announced today a 5-year plan to promote the development of new antimicrobials for drug-resistant bacteria. The plan includes changes to the reimbursement system, which may make drugs more profitable for developers, as well as some nontraditional treatment approaches.

Patients who were negative for hepatitis C virus and received HCV-infected kidneys and antiviral treatment were clear of the disease and experienced good renal function up to a year after transplantation, according to study results recently published in the Annals of Internal Medicine.

Kidney amyloid A-type amyloidosis was strongly associated with injection heroin use in the Pacific Northwest, according to research appearing in the Clinical Journal of the American Society of Nephrology.

Kidney transplant with a kidney infected with hepatitis C virus, followed by treatment for the hepatitis C, was effective and reduced costs compared with transplant with an uninfected kidney after hepatitis C treatment, according to new research published in Annals of Internal Medicine.

Continuous antibiotic prophylaxis was effective in preventing recurrent urinary tract infections among clean intermittent self-catherization users who are at risk for the infection, according to study findings recently published in The Lancet Infectious Diseases. However, researchers observed increasing levels of antibiotic resistance with prophylaxis use, which they said “limits the appeal” of the prevention strategy.

Children with vesicoureteral reflux, a condition in which urine flows backward from the bladder to the kidneys, are at increased risk for urinary tract infections; however, those who receive prophylaxis are 6.4 times more likely to develop multidrug-resistant infections, according to a recent meta-analysis.