Bone and Mineral Metabolism Disorders News

Compared with standard targets, lower serum phosphate levels led to smaller changes in coronary artery calcification scores, suggesting stricter phosphate control may delay calcification progression for patients on hemodialysis.

Adding to data from clinical trials demonstrating the efficacy of sucroferric oxyhydroxide in phosphate management for patients on hemodialysis, researchers from Spain have identified several benefits of the drug in “real-world” settings.

Patients categorized as frail and who were undergoing evaluation for kidney transplantation were “more likely” to have care partners who were also frail, according to a study.

An analysis of participants enrolled in the Chronic Renal Insufficiency Cohort study showed those with low or high serum magnesium levels had greater mortality rates.

A study of patients with chronic kidney disease showed no direct relationship between lower eGFR levels and metabolic rate, leading researchers to suggest other factors may play a bigger role in differences in energy metabolism.

The FDA has approved Alnylam Pharmaceuticals Inc.’s lumasiran, known as Oxlumo, for the treatment of primary hyperoxaluria type 1 in both adults and children.

Patients with heart failure and reduced ejection fraction who were randomized to dapagliflozin had half the risk of moderate to severe hyperkalemia vs. placebo, according to results of the DAPA-HF trial presented at ASN Kidney Week.

From 2008 to 2015, prescriptions for vitamin D sterols trended downward while prescriptions for phosphate binders and cinacalcet increased for patients with kidney failure at 359 facilities affiliated with Dialysis Clinic Inc.

Kidney disease guidelines paired with checklist and care coordination logs were linked to improved results in patients with mineral and bone disorders, according to a presentation.

Improved potassium levels impacted the physical and/or mental well-being of patients managing hyperkalemia, according to study results presented at the American Nephrology Nurses Association National Symposium.