Acute Kidney Injury News

The FDA has granted fast track designation for development of ASP1128, an investigational compound by Astellas Pharma Inc. for patients at risk of developing acute kidney injury after coronary artery bypass or valve surgery, according to a company press release.

SAN FRANCISCO — A hydration regimen guided by urine flow rate was superior to a strategy guided by left ventricular end-diastolic pressure for reducing contrast-induced acute kidney injury in patients undergoing PCI, according to the results of the REMEDIAL III study.

The FDA has accepted an investigational new drug application to evaluate the efficacy of Elysium Health’s cellular health supplement in preventing acute kidney injury in patients who undergo cardiac surgery.

Recently published findings from Canada suggest use of hemodialysis for children hospitalized with acute kidney injury has increased in 2 decades and is associated with a high risk for short-term mortality.

Higher plasma uric acid levels were not associated with increased risk for acute kidney injury in patients admitted to the ICU, nor did such levels contribute to adverse clinical outcomes following renal replacement therapy for patients who had AKI, according to a published study.

Nephritis, clinical trials and biomarkers rank highest among research priorities related to childhood-onset systematic lupus erythematosus, according to a survey of rheumatologists, dermatologists and nephrologists published in Pediatric Rheumatology.

A tool that uses artificial intelligence and a machine learning algorithm enhanced the performance of existing tests for predicting acute kidney injury in certain high-risk populations, according to a published study.

A risk model accurately categorized patients with an inpatient episode of acute kidney injury into clinically distinct groups according to likelihood of either death or recovery of kidney function and ability to discontinue dialysis after hospital discharge, according to a published study.

Prolonged maintenance therapy with cyclosporine was associated with ongoing complete responses in a cohort of patients with lupus nephritis, according to recent findings presented at the EULAR Annual Congress.

The rate and speed of fluid removal during dialysis for patients with AKI can influence the risk of mortality, according to a study published by University of Pittsburgh School of Medicine researchers.