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November 07, 2022
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VIDEO: Early diagnosis of CKD can slow eGFR decline

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In this video from ASN Kidney Week, Navdeep Tangri, MD, PhD, discusses the results of the REVEAL CKD study.

“In this study, we took a look at medical records and found that patients in the United States — 27,000 patients with [chronic kidney disease] CKD stage 3 — had a long lag in their lab confirmation of the diagnosis and the actual diagnosis recorded in the chart,” Tangri told Healio. “The lag was almost 1.5 years.”

Analyses revealed that patients experienced a significant slowing in eGFR decline following a CKD stage 3 diagnosis. Further, the median eGFR decline among patients in the 2 years prior to diagnosis was –4.12, and then it became –0.30 in the 2 years after the diagnosis. Tangri suggested this improvement was due to improved care after diagnosis.

“The main finding of this study is that making a diagnosis of CKD in the chart is important even if you have lab confirmation and around half the time, this just doesn’t happen,” Tangri said.