COVID-19 vaccine demonstrates effectiveness in transplant recipients
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Fully vaccinated transplant recipients see an almost 80% reduction in COVID-19 incidents compared with transplant recipients who are not fully vaccinated, according to a study published in Transplant Infectious Disease.
“We aimed to assess the incidence rate of coronavirus disease 2019 (COVID-19) in vaccinated [vs.] unvaccinated (solid organ transplant recipients) SOTRs at our center,” Saima Aslam, MD, MS, of the University of California, San Diego (UCSD), and colleagues wrote.
After collecting clinical data from the department of medicine at UCSD, Aslam and colleagues evaluated individuals’ age, sex, vaccination type and status. The study included 2,151 SOTRs from a single center; 64.6% of participants were men and the median age was 57 years. There was a test group of 912 fully vaccinated individuals and a control group of 1,239 nonvaccinated or partially vaccinated individuals.
The vaccinated group had an incidence rate of 0.065 per 1,000/person days at risk compared with the control group that had an incidence rate of 0.34 per 1,000/person days at risk, according to the study.
During the study period (January through June 2021), there were 65 cases of COVID-19 among the two groups. The vaccinated group had four cases, but the control group had 61 cases and two COVID-19-related deaths, researchers wrote.
Study limitations included the single-center cohort and possibility of underreporting of vaccination status, according to researchers.
“Lastly, almost half of the study population was unvaccinated, and thus there is a great need to improve outreach activities in the transplant community to promote COVID-19 vaccination,” Aslam and colleagues wrote.
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Aslam S, et al. Transpl Infect Dis. 2021;doi:10.1111/tid.13705.
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