Exercise associated with reduced risk of chronic kidney disease
Click Here to Manage Email Alerts
Participants who engaged in more frequent physical activities had a lower risk for chronic kidney disease compared with participants who were inactive, according to a study published in American Journal of Kidney Diseases.
“Physical activity is associated with reduced risk of developing chronic illnesses such as cardiovascular disease, diabetes, and hypertension, which have similar risk profiles and underlying pathophysiology as CKD [chronic kidney disease],” Kaushik Parvathaneni, BS, and colleagues wrote. “A better understanding of the relationship between physical activity and CKD may help guide CKD prevention efforts that target modifiable lifestyle factors.”
In a prospective cohort study, Parvathaneni and colleagues administered the Baecke Physical Activity Questionnaire to 14,537 participants from 1987 to 1989, used the 2018 Physical Activity Guidelines for Americans to categorize participants’ activity level (inactive: 37.8% of participants; insufficiently active: 24.2% of participants; active: 22.7% of participants; highly active: 15.3% of participants) and determined participants’ estimated glomerular filtration rate (eGFR). Participants were 45 to 65 years old and attended seven follow-up visits from 1990 to 2019. Researchers included data from Black and white participants only because they said there were “low numbers” of other groups. Study outcomes included incidence of CKD, hospitalization or mortality related to CKD, and end-stage renal disease.
In an adjusted analysis of 14,537 participants, physical activity correlated with a lower risk for CKD compared with participants who were inactive (insufficiently active: HR = 0.95; 95% CI, 0.88-1.22; active: HR = 0.93; 95% CI, 0.86-1.01; highly active: HR = 0.89; 95% CI, 0.88-1.02). During the follow-up period, 33.2% of participants developed CKD and 7,109 participants died. Activity level was associated with a lower risk for mortality (insufficiently active: HR = 0.92; 95% CI, 0.86-0.98; active: HR = 0.91; 95% CI, 0.85-0.97; highly active: HR = 0.86; 95% CI, 0.80-0.93).
“[G]reater physical activity was associated with higher eGFR in older age, even when physical activity was assessed 25 years prior,” researchers wrote, adding that in the context of other literature, “these results suggest that the benefit of physical activity in adults may span both middle and older adulthood.”
Collapse
Read more about
Click Here to Manage Email Alerts