May 22, 2018
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Patients spend more time in early stages of CKD than in later stages

According to a study published in the Clinical Journal of the American Society of Nephrology, patients with chronic kidney disease spend a longer period of time in earlier stages of the disease than in later stages and the amount of time varies with risk factors.

Elaine Ku

“This study highlights the large variations in time spent in different stages of [chronic kidney disease] CKD based on the presence (or absence) of a variety of risk factors, and the potential advantages of thinking about progression of kidney disease using a time-based approach that might be easier for patients to understand and motivate better compliance with therapy if appropriate,” Elaine Ku, MD, co-author of the study from the University of California, told Healio Nephrology.

Researchers looked at 3,682 participants of the Chronic Renal Insufficiency Cohort and used mixed models to estimate person-specific trajectories of function to estimate time spent in each stage of CKD. A median of 7.9, 5, 4.2 and 0.8 years were spent in stages 3a, 3b, 4 and 5, respectively, among patients with CKD.

Investigators found the amount of time spent in stage 3a was shorter for older patients compared with younger patients; however, the opposite was true in stage 3b. Compared with white patients, investigators found black and Hispanic patients had a shorter duration of time in stages 3a and 3b.

 

Disclosures: The authors report no relevant financial disclosures.