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Study: First infection-related hospitalization leads to recurrent infections in HHD patients
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New Orleans - Daily home hemodialysis patients with a fistula had a higher risk of a first infection-related hospitalization (IH) than in-center hemodialysis patients with a fistula, according to an abstract presented by Eric D. Weinhandl, PhD, and Allan J. Collins, MD, from NxStage Medical Inc., at the American Society of Nephrology's Kidney Week 2017.
The researchers analyzed data from 4,304 home hemodialysis (HHD) patients who completed training with the NxStage System One between 2006-2012, and 46,988 in-center (IHD) patients using the U.S. Renal Data System.
HHD patients had a 24% higher risk of a first IH compared to IHD patients. For HHD and IHD patients, the cumulative incidence of an IH increased with each additional IH. HHD patients had similar or slightly lower risk of recurrent IH.
“In both dialytic settings, each additional IH discharge increased the risk of another IH. Less time to first IH in HHD patients prematurely sets in motion the cycle of increasing risk, ultimately manifesting as a higher IH rate on HHD versus IHD. Attention should be devoted to prevention of the first infection on HHD.” - by Rebecca Zumoff