Gastrointestinal Infections News

The number of new cases of type 1 diabetes among young Australian children declined after oral rotavirus vaccination was added to the routine immunization schedule for children aged 6 weeks and older, according to research published in JAMA Pediatrics.

Patients hospitalized with an Enterobacteriaceae bloodstream infection who transitioned to oral step-down therapy demonstrated similar 30-day mortality rates and a modest reduction in the duration of hospital stay to those who continued IV therapy, according to research published in JAMA Internal Medicine.

I followed a somewhat circuitous route to a career in ID. In medical school and residency, I was strongly drawn to oncology but got a bit distracted by also falling in love with viruses, especially retroviruses. I worked in research virology labs all through college and medical school, and as retroviruses were considered as potentially causing common cancers in humans, that research was typically found not in ID but rather in oncology divisions. I came to UCSF in 1978 for my oncology fellowship and to work in Jay Levy’s retrovirus lab. But when an ID giant, Merle Sande, offered me the chance to start a medical oncology division at San Francisco General Hospital immediately following the end of my training, I eagerly accepted. I left retrovirus research forever, only to walk into the very beginning of the AIDS epidemic on July 1,st 1981, when I saw the first Kaposi sarcoma KSpatient admitted to SFGH. I started the world’s first comprehensive AIDS clinic with Connie Wofsy, my ID counterpart in 1983 and when HIV was discovered (in part by Jay), I realized I might get back to my favorite viruses! While I still feel as if part of me is in oncology, my community is clearly ID! Definitely hooked on ID!

Modern medicine may face dangerous setbacks if the antimicrobial market does not see a positive shift soon, experts agree.

Patients with complete response to hepatocellular carcinoma and underwent direct-acting antiviral therapy for hepatitis C had similar rates of cancer recurrence compared with patients who did not receive DAA therapy, according to a study published in Gastroenterology.

Toxin-positive Clostridioides difficile infection, or CDI, tended to be more severe than CDI that was detected through nucleic acid amplification tests, but researchers found no differences in CDI-related complications or mortality rates between cases that were detected using either approach, according to a recent study.

A research consortium across multiple institutions has begun enrolling patients in a clinical trial examining whether fecal microbiota transplantation by enema is safe and effective in preventing recurrent Clostridium difficile-associated disease, according to a press release.

HepVu — an interactive online resource designed to visualize data on the U.S. hepatitis C epidemic — announced the release of new interactive maps that provide state-level estimates of HCV infections, according to a press release and online presentation.

Researchers discovered a substantial proportion of patients with newly diagnosed cancer and concurrent hepatitis C or hepatitis B were unaware of their viral infection and many had no identifiable risk factors, according to a recently published study.

A decentralized, nurse-led model of hepatitis C care with direct-acting antivirals was significantly effective and led to high levels of sustained virologic response in a large cohort of inmates, according to a recently published study.