Infectious Disease News Current Issue

The following articles appeared in the print edition of Infectious Disease News.

Table of Contents

• Global rise in dengue warrants improved prevention, control methods
• Australia to end welfare payments for families rejecting vaccination
• CDC enrolling 6,000 Sierra Leone HCWs in Ebola vaccine trial
• CDC helps African Union launch African CDC
• Date syrup contains antibacterial compounds
• FDA launches Expedited Access Pathway program for devices
• Gilead submits NDA for HIV combination therapy candidate
• Microneedle patch could increase measles vaccinations
• Novel mechanism and potential treatment strategies for CVD in HIV patients Steven K. Grinspoon, MD
• Syphilis: An old, easily diagnosed and treated disease … on the rise Donald Kaye, MD, MACP; Matthew E. Levison, MD, FACP
• FDA grants new breakthrough therapy designations for grazoprevir/elbasvir
• FDA grants priority review for oral, interferon-free treatment of HCV genotype 4
• Abnormalities related to C. gattii may be slow to resolve
• Amoxicillin/probenecid effectively treats syphilis in HIV patients
• Antimicrobial stewardship program reduces antibiotic use
• Azithromycin ineffectively treats macrolide-resistant M. genitalium
• Beta-lactam performs similarly to preferred treatments for CAP
• BSTI testing rates low among sexually active HIV population
• Bundled TB testing, on-site provider training improves disease detection, outcomes
• C. difficile cases highest in Northeast, springtime
• Campylobacteriosis outbreak linked to undercooked chicken livers
• CRISPR system opens window to C. albicans pathology
• Diagnostic tool may help risk-stratify suspected Ebola cases
• Duodenoscopes cause of E. coli outbreak in Washington
• Environment less important in hospital transmission of CRE
• Exposure to bleach increases risk for respiratory infections
• Few mutations implicated in transmission of drug-resistant HIV
• Flu vaccine did not modify flu severity during 2012-2013 season
• Group therapy improves depression outcomes among adults with HIV
• High blood pressure more common than previously believed in children with HIV
• HIV accelerates development of age-related illnesses
• HIV infections surge in Indiana
• HIV self-testing may be cost-effective in low-income countries
• Hospitalization rates for pediatric osteoarticular infections rise
• In utero exposure to Retrovir linked to congenital heart defects
• Iron increases malaria risk during pregnancy
• Kidney transplant survival rate found worse in recipients with HCV vs. HIV
• Model accurately predicts rapid response in HCV at 4 weeks
• Molecular switch deactivates HCMV; may benefit organ transplantation
• More than 90% of hand hygiene opportunities missed during anesthetic procedures
• MRSA infections linked with prior nasal colonization at VA hospital
• N. lactamica may suppress meningococcal outbreaks
• Newer HCV medications yield health benefits at more reasonable cost
• Nitrofurantoin less effective than other antibiotics for UTI patients
• Novel syphilis test distinguishes active vs. past infections
• Online content for Ebola exceeds suggested reading levels
• Oral antibiotics showed similar efficacy, safety to injectable antibiotics for bacterial infections
• Persistent H. pylori in childhood linked to specific strain profiles, future disease
• Point-of-care fingerstick CRAG provides low-cost, rapid meningitis diagnosis
• Portable mass spectrometry technique accurately detects C. difficile in unprocessed stool
• Respiratory virus infection before HCT increases mortality
• Ribotype 027 increases risk for severe C. difficile infection, mortality
• Rise in health data breaches driven by criminal activity
• Routine rotavirus vaccine reduced disease circulation in US children
• Simpler forecasting models do not account for variability, uncertainty
• Some weight gain after starting ART may reduce mortality
• T-cell biomarkers distinguish active, latent M. tuberculosis infection
• Text messages track adverse events after flu vaccine in HCP
• US affected by widespread antibiotic shortages from 2001-2013
• Validated risk score for CKD may guide HIV treatment decisions
• ANRS CO22: SVR4 rates near 100% for sofosbuvir/daclatasvir in genotype 1
• C-EDGE: Grazoprevir/elbasvir regimen yields high SVR rates in patients with HCV
• Chikungunya common among US volunteers in Dominican Republic
• C-SALT: Child-Pugh B patients respond to grazoprevir/elbasvir
• EASL releases, outlines 2015 HCV recommendations
• HBV vaccine unaffected by diabetes
• Previous treatment failures respond to 24 weeks of Harvoni
• Prompt contact tracing disrupts Ebola virus transmission into Senegal
• Providers need to continually promote HPV vaccine to parents
• RUBY-I: Preliminary study shows safety of 3D + ribavirin in CKD
• Tdap appears safe for pregnant women, infants
• Tour bus surveillance identifies potential norovirus cases at Yellowstone
• U.K. residents swimming in coastal waters may ingest resistant E. coli
• Beyond ART: Primary care pharmacotherapy for people living with HIV Leah Molloy, PharmD