Infectious Disease News Current Issue

The following articles appeared in the print edition of Infectious Disease News.

Table of Contents

• US hospitals step up training, preparation for Ebola
• Canadian supercomputer to simulate potential Ebola treatment options
• CDC: 30% of people with HIV achieved viral suppression
• Chikungunya persists in Caribbean; travellers remain at risk
• Doravirine HIV treatment resulted in fewer adverse events
• Plague outbreak confirmed in Madagascar
• Three-drug regimen during pregnancy more protective against vertical HIV transmission
• Web traffic shows promise as predictor for disease outbreaks
• Infectious disease research requires big picture, collaborative approach Louie Coffman; John Aitchison, PhD
• Ebola in the news Donald Kaye, MD, MACP; Keith S. Kaye, MD, MPH
• Gilead submits new drug application for single-tablet HIV treatment
• Isavuconazole granted orphan drug status
• AAP updates guidelines for diagnosis, management of bronchiolitis
• Amoxicillin-associated diarrhea, candidiasis may be underreported
• Anti-HCV prevalence higher in MSM injection drug users vs. nonusers
• Atazanavir associated with higher triglycerides, fat levels vs. darunavir
• Coding variations may have resulted in discrepancy in sepsis trends
• Comprehensive care coordination improved HIV outcomes
• Congenital HHV-6 may negatively affect neurodevelopment
• Converted for-profit hospitals improved revenues, not outcomes
• Co-trimoxazole linked to sudden death in older patients on renin-angiotensin inhibitors
• Emtricitabine yielded better virologic outcomes than lamivudine in first-line ART
• HAV hospitalization rate decreased in US from 2002 to 2011
• HBV/HCV in mothers led to increased risk for neurological outcomes in infants
• High rate of culture conversion observed with bedaqualine for TB
• HIV associated with increased risk for age-related events
• HIV, STIs prevalent among male sex workers in Mexico City
• HIV transmission linked to shared manicure instruments
• In utero exposure to ART posed little to no risk for congenital anomalies
• Increased CV risks seen with azithromycin, moxifloxacin
• Isoniazid preventive therapy reduced TB risk in adults with HIV
• Leprosy incidence greater among foreign-born individuals
• Livestock-associated MRSA strain present in hospitals
• Long-term PPI use reduced microbial diversity, increased risk for CDI
• MERS outbreak in Saudi Arabia tied to nosocomial transmission
• Most diarrhea cases in transplant recipients had no infectious etiology
• Multiple BPG doses did not improve treatment response in HIV patients with syphilis
• Novel, resilient antibiotic discovered in fungus
• Pathogens causing skin, soft tissue infections found in hidradenitis suppurative lesions
• PCPs chose inappropriate antibiotics based on cure rate beliefs, patient pressure
• PCV7, PCV13 linked with fewer pneumonia hospitalizations
• Pre-emptively updating flu vaccine strains may improve effectiveness
• Psychological stress did not increase herpes zoster risk
• Quality indicators may be useful for antibiotic stewardship
• Small percentage of MSM with gonorrhea had persistent disease DNA after therapy
• Surveillance algorithm identified onset of influenza outbreaks
• Survival among HCV patients with SVR reaches that of general population
• TB genome play role in relapse, reinfection
• Tdap, MCV4 vaccination uptake improved compared with HPV vaccination
• Universal rectal screening increased chlamydia detection in high-risk women
• Vaccination not associated with long-term MS risk
• Vector-borne, zoonotic diseases pose threat to soldiers in Afghanistan
• Viral hemorrhagic fever case in US soldier highlights need for control measures
• Virologic failure rate declined significantly in France over 15 years
• WHO: Progress towards measles elimination stalling
• ZMapp analysis could improve effectiveness of Ebola treatments
• Leishmaniasis outbreak in Lebanon most prevalent in Syrian refugees
• ACIP accepts proposed updates to typhoid vaccine statement
• ACIP votes to update general recommendations
• Birth cohort screening more accurate in detecting HCV vs. standard method
• Chagas disease on the rise, acquired locally among Texas blood donors
• Check Hep C program effective in identifying HCV in New York
• Combination treatment safe, effective among African children with malaria
• C-SWIFT: Shortest duration of triple therapy for HCV only effective in small percentage of patients
• C-WORTHY: Grazoprevir/elbasvir regimen yielded high SVR rates in patients with HCV genotype 1
• Dialysis safely delivered to patient with Ebola
• Levofloxacin after kidney transplantation did not prevent infection
• Long-term efficacy, safety of tenofovir disoproxil fumarate for chronic HBV confirmed
• P. knowlesi malaria cases increasing in Malaysia
• Palivizumab prophylaxis for RSV requires more definitive data
• Serologic testing, guideline adherence low among veterans with HBV in VA care
• TURQUOISE-II: Demographics, viral factors did not predict SVR after 3D regimen
• Two studies show promise for 8-week treatment with GS-5816
• UNITY 2: Fixed-dose combination with BMS-791325 yields SVR12 in treatment-naive, experienced patients
• HIV and mental illness: Are drug interactions a barrier to effective therapy? Kati Shihadeh, PharmD, BCIDP; Corey Ball, PharmD