Infectious Disease News Current Issue

The following articles appeared in the print edition of Infectious Disease News.

Table of Contents

• Norovirus vaccine development accelerates after success against rotavirus Caitlyn Stulpin
• 1 in 10 children missed lifesaving vaccines in 2018
• UK loses measles-free status; US on the brink
• 6 treatments per year? Injectable HIV regimen effective when given every 2 months
• CDC OKs new two-tier testing algorithm for Lyme disease
• Core stewardship intervention feasible at community hospitals
• Migrants detained at border will not be vaccinated against flu
• NIH launches delamanid trial for MDR-TB prevention
• Q&A: FMT for fecal decolonization of antibiotic-resistant organisms
• Q&A: Insights from recreating the 1918 flu virus
• Syphilis cases reach all-time high in Europe, up 70% in 7 years
• Two of four Ebola treatments prove effective in DRC trial
• What are the world’s top vaccine priorities?
• Which norovirus vaccine candidate or approach holds the most promise?
• Developing new-generation antibiotics to curb antibiotic resistance Farokh Dotiwala, MBBS, PhD
• Nipah virus: Going from bat to worse Donald Kaye, MD, MACP; Thomas M Yuill, PhD
• FDA approves Nabriva’s Xenleta to treat CABP in adults
• Pretomanid, first TB drug developed by non-profit, gets FDA approval for resistant infections
• Infections linked to thawing show importance of Arctic surveillance
• Hooked on ID with Raghavendra Tirupathi, MD, FACP Raghavendra Tirupathi, MD, FACP
• ‘5 Moments of Antimicrobial Prescribing’ metric increases prescribing appropriateness
• 16% of patients with antimicrobial-resistant bacteria do not have prior antimicrobial exposure
• 33% of animal-use probiotics contain pathogens; spillover to humans documented
• Accounting for presence of concurrent central lines decreases CLABSI rates
• ‘All the characteristics’: Hepatitis E is a neglected tropical disease, experts say
• Antimicrobial stewardship teams, ID consults reduce S. aureus bacteremia
• Around 1,500 MERS cases, 500 deaths averted since 2016
• ART does not affect vaginal microbiome, study suggests
• Automated EMR tool improves antimicrobial stewardship
• Bacterial species in vaginal microbiota may increase risk for T. vaginalis
• Bednet monitor shows families’ irregular use of malaria prevention strategy
• C. trachomatis may raise risk for precancerous anal lesions in patients with HIV
• CDI incidence rising in veterans under age 65, VA data show
• Chlamydia vaccine shows promise in phase 1 trial
• Clinical uptake of new anti-CRE agents ‘steady but slow’
• Dolutegravir-based regimens noninferior to standard HIV care, studies show
• Drug-resistant malaria spreads in Asia, prompting calls for new treatments
• EHRs can help identify potential PrEP candidates
• Electronic hand hygiene monitoring systems ‘vary substantially’
• Flu vaccine associated with reduced risk for death, stroke in elderly ICU survivors
• Global warming may have contributed to emergence of C. auris
• Herd immunity drives down invasive pneumococcal disease in adults
• Hospital-acquired C. difficile linked to higher costs, longer stay
• Inappropriate urine culture practices contribute to overdiagnosis of CAUTIs
• Incidence of West Nile virus neuroinvasive disease increased 25% in 2018
• Infants ‘naturally immunized’ against toxigenic C. difficile
• Investigation links outbreak of S. paucimobilis bacteremia to drug diversion
• Malaria vaccine protects against severe malaria 7 years after vaccination
• MERS-CoV vaccine shows promise in phase 1 trial
• New findings provide additional evidence of AFM, enterovirus link
• Novel skin antiseptic ZuraGard matches efficacy of ChloraPrep
• One-third of children exposed to Zika in utero show neurological problems
• Opportunity for collaboration: ASPs and palliative care providers
• Patients treated for TB experience higher mortality than general population
• Pharmacist-led program a feasible strategy for PrEP uptake
• Pneumocystis pneumonia prophylaxis guidelines would be ‘helpful,’ ID docs say
• Poor outcomes, unidentified causes still common in encephalitis cases
• Procalcitonin-guided ASP recommendations shorten antibiotic therapy at community hospital
• Researchers predict 60% of globe will be at risk for dengue by 2080
• RSV burden extends beyond 5 years after acute infection
• Secondary syphilis more common in MSM who practice receptive anal intercourse
• Teen HPV vaccine uptake increases with provider recommendation
• ‘Unexpected’: Centers following CDC framework use more of certain antibiotics
• HOPE trial: Dapivirine vaginal ring reduces HIV risk by estimated 39%
• Merck evaluating novel HIV drug as implant for long-lasting PrEP
• Preventing and treating flu in immunocompromised patients: 2019-2020 update Leah Molloy, PharmD; Selena Warminski, PharmD