Antimicrobials News

Achaogen, maker of the antibiotic Zemdri, announced that it has filed for chapter 11 bankruptcy protection in Delaware and is seeking authorization to pursue an auction and sale.

A hospital in Israel used bacteriophages and antibiotics to successfully treat a multidrug-resistant left tibial infection in a man who was injured in an auto accident, saving his leg from amputation, researchers said.

Physicians and other prescribers at a large children’s hospital generally favored the hospital’s antimicrobial stewardship program but found parts of it to be inefficient, according to survey results published in Infection Control & Hospital Epidemiology.

The IV formulation of fosfomycin was found to be effective in treating complicated UTIs, including acute pyelonephritis, compared with IV piperacillin-tazobactam, according to research published in Clinical Infectious Diseases

A study published in Pediatrics revealed that children with acute respiratory infections who are treated through direct-to-consumer telemedicine visits are significantly more likely to receive antibiotics. These children, according to the researchers, are also less likely to receive guideline-based antimicrobial treatment.

A recent study found that long-term cotrimoxazole treatment reduces mortality and morbidity in children with HIV by altering their gut microbiome and immune activation.

After conducting a systematic review of published studies, researchers said they were unable to identify the best strategy to improve clinician adherence to evidence-based interventions to prevent surgical site infections, or SSIs. However, they said successful approaches tended to employ multifaceted strategies that included engagement, education, execution and evaluation.

The protective mucus that coats young fish contains bacteria that demonstrate activity against some pathogens, including MRSA, according to findings presented at the American Chemical Society National Meeting and Exposition.

A new public health awareness campaign is focusing on antibiotic overuse in Kentucky, the U.S. state with the highest rate of antibiotic use.

Treating uncomplicated UTIs using narrower-spectrum agents appears to limit the development of antibiotic resistance locally, according to findings from a case-controlled analysis conducted over 7 years at a health care system in Colorado.