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Antimicrobials News
Maribavir shows promise against CMV in transplant recipients
Twice-daily maribavir demonstrated similar efficacy as valganciclovir in clearing cytomegalovirus viremia in hematopoietic-cell or solid-organ transplant recipients, according to results from a phase 2 trial published today in The New England Journal of Medicine.
Broad-spectrum antibiotics may weaken flu vaccine response
Healthy adults who take broad-spectrum antibiotics may impair their body’s immune response to influenza vaccination, according to findings from a small study published in Cell.
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Implementing ASP via telehealth represents a ‘viable’ strategy
An antimicrobial stewardship program implemented via telehealth at a community hospital in western Pennsylvania decreased broad-spectrum antibiotic use, increased infectious diseases consultations and lowered costs associated with antimicrobial therapy.
Stewardship-focused rounds improve guideline adherence among medical residents
Adding dedicated, stewardship-focused rounds to medical residents’ curriculum leads to increased guideline adherence, especially for duration of therapy, according to a study published in Infection Control & Hospital Epidemiology.
ID physicians prefer oral antibiotics for treatment of patients with bacteremia
A survey among members of the Infectious Diseases Society of America’s Emerging Infection Network showed that the majority of adult infectious disease physicians would shift patients with both gram-negative and gram-positive bacteremia to oral antibiotics for treatment.
Fluoroquinolones pose risk for aortic, mitral regurgitation
Current and recent use of fluoroquinolones, but not past use, were associated with elevated risk for aortic and mitral regurgitation, researchers reported.
Maternal quinolone exposure increases risk for resistant infection in child
Children whose mothers received antimicrobial therapy with quinolones faced an approximately 50% increased risk for quinolone-resistant bacteriuria, according to a study of more than 40,000 children published in Clinical Infectious Diseases.
Novel drug combination noninferior to meropenem for treating cUTIs
A novel combination that includes ceftriaxone, sulbactam and disodium EDTA, or CSE, was noninferior to meropenem for the treatment of complicated UTIs, or cUTIs, caused by extended-spectrum beta-lactamase-producing, or ESBL-producing, gram-negative bacteria, according to results from the phase 3 PLEA trial.
Fluoroquinolone use decreases following FDA black box warning
The FDA black box warning on fluoroquinolones that was issued in 2016 resulted in a significant, further decline in use at 29 southeastern U.S. hospitals, according to a recent study published in Infection Control and Hospital Epidemiology.
Survey shows low uptake of surgical antimicrobial prophylaxis guidelines
A survey conducted within the Society for Healthcare Epidemiology of America Research Network showed that only 30.8% of hospitals have fully adopted recommendations against the use of surgical antimicrobial prophylaxis after an incision has been closed.
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Headline News
Q&A: Cuts to 2025 physician fee schedule yield ‘catastrophic’ impacts to patient access
November 11, 20246 min read -
Headline News
Daily oral semaglutide confers weight loss vs. placebo; similar vs. weekly injectables
November 11, 20243 min read -
Headline News
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November 11, 202410 min read