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VIDEO: Next-generation test improves pathogen identification in sepsis

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SAN DIEGO — Simone Thair, PhD, postdoctoral research fellow at Stanford University Medical Center, reviews data from a late-breaker presentation at IDWeek that showed the Karius plasma next-generation sequencing assay was associated with a nearly threefold improvement in pathogen detection among patients with sepsis compared with blood culture.

According to Thair, the Karius assay can produce results faster than techniques that are currently used to identify pathogens in septic patients. It can also detect fastidious organisms that are hard to culture.

“This is a major improvement [and] is really geared toward that population of 30% to 40% of people who die from sepsis who never had a blood culture come back positive at all,” she says.

Reference:

Thair S, et al. LB-5. Presented at: IDWeek; Oct. 4-8, 2017; San Diego.

Disclosure: Thair reports no relevant financial disclosures.