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Surveillance of malaria resistance essential for proper antimicrobial use in Peru
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PHILADELPHIA — Findings from a study conducted in Peru indicate significant therapeutic implications for the management of enterocolitis, and continued surveillance across all areas in the country is needed to guide efficient antimicrobial use, according to a presenter here.
Researchers assessed 4,652 stool samples for Campylobacter species types from 2001 to 2010 and tested susceptibilities to azithromycin, ciprofloxacin and erythromycin.
Eighty-two percent of isolates tested positive for Campylobacter jejuni, 11% for C. coli and 7% for other Campylobacter species types.
During the 10-year study period, the prevalence of ciprofloxacin resistance increased from 46% to 92% among isolates obtained from Lima. Similarly, resistance to ciprofloxacin increased from 50% to 86% in the Cusco region of Peru and from 19% to 38% in isolates obtained from Iquitos.
Only 1% of isolates from Lima and 2% of isolates from the Cusco region were resistant to azithromycin. Resistance to erythromycin was only 1% among isolates from Lima and none from the Cusco region.
Conversely, the researchers observed an increase in azithromycin resistance from 3% to 14% and erythromycin resistance from 3% to 17% in isolates from Iquitos, Peru.
For more information:
- Pollett S. #79. Presented at: the American Society of Tropical Medicine and Hygiene 60th Annual Meeting; Dec. 4-8, 2011; Philadelphia.
Disclosure: The researchers report no relevant financial disclosures.
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